A Member of the Rieveschl Laboratories for Mass Spectrometry
RAMM Software Update (v2) now available
RoboOligo Software now available
Learn more about the National Academies Consensus study on Sequencing the Epitranscriptome
Selected Recent Publications
Robert L. Ross, Ningxi Yu, Ruoxia Zhao, Andrew Wood and Patrick A. Limbach. “Automated Identification of Modified Nucleosides during HRAM-LC-MS/MS using a Metabolomics ID Workflow with Neutral Loss Detection” Journal of the American Society for Mass Spectrometry (2023) doi:10.1021/jasms.3c00298.
Manasses Jora, Daniel Corcoran, Gwenn G. Parungao, Peter A. Lobue, Luiz F. L. Oliveira, George Stan, Balasubrahmanyam Addepalli, and Patrick A. Limbach “Higher-Energy Collisional Dissociation Mass Spectral Networks for the Rapid, Semi-automated Characterization of Known and Unknown Ribonucleoside Modifications” Analytical Chemistry (2022) 94(40):13958-13967. doi: 10.1021/acs.analchem.2c03172. PMID: 36174068.
"Chemical Amination/Imination of Carbonothiolated Nucleosides During RNA Hydrolysis” Jora M, Borland K, Abernathy S, Zhao R, Kelley M, Kellner S, Addepalli B, Limbach PA. Angew Chem Int Ed Engl. (2021) 60 3961-3966. DOI: 10.1002/anie.202010793. PMID: 33125801
“Oligonucleotide Analysis by Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry in the Absence of Ion-Pair Reagents” P.A. Lobue, M. Jora, B. Addepalli, P.A. Limbach, Journal of Chromatography A (2019) DOI: 10.1016/j.chroma.2019.02.016. PMID: 30772056.
“Transfer RNA Modification Profiles and Codon Decoding Strategies in Methanocaldococcus jannaschii” N. Yu, M. Jora, B. Solivio, P. Thakur, C.G. Acevedo-Rocha, L. Randau, V. de Crécy-Lagard, B. Addepalli, P.A. Limbach, Journal of Bacteriology (2019) 201 e00690-18. DOI: 10.1128/JB.00690-18 PMID: 30745370.
“RNAModMapper: RNA modification mapping software for analysis of mass spectrometry data”, N Yu, C Wetzel, X Cao, PA Limbach, Analytical Chemistry (2017) doi: 10.1021/acs.analchem.7b01780 PMID: 28942636
June 2 - 6, 2024
Future ASMS conference in Anaheim, CA
Upcoming Events
Publications/Software/Databases/Book Chapters
Software
RNA Mod Mapper - Ningxi Yu’s software for automated annotation of RNA mass spectrometry data.
RoboOligo - Paul Sample’s software for de novo and manual annotation of RNA mass spectrometry data.
MO Predict - Software developed in the Limbach Group to expand the capabilities found on-line in Mongo Oligo.
Books and Contributed Chapters in Edited Books
• Analytical Characterization of Oligonucleotides by Mass Spectrometry Chapter 4 in Analysis of Oligonucleotides and Their Related Substances edited by D. Elder, G. Okafo, and M. Webb (2013)
• Matrix-Assisted Laser Desorption/Ionization in VOLUME V. Bioanalytical Approaches: MS, NMR, Isotope Methods, Spectroscopy, Ligand-Binding, and Other Analytical Chemistry Methods of the Encyclopedia of Drug Metabolism and Interactions edited by David C. Muddiman and Lucinda Cohen (2012)
• Analysis by Hydrophilic Interaction Chromatography - Chapter 16 in Handbook of Analysis of Oligonucleotides and Related Products edited by J. Bonilla and S. Srivatsa (2010)
• Mass Spectrometry of Nucleosides and Nucleic Acids - edited by Joseph A Banoub and Patrick A Limbach (2010)
• A Comparison of MALDI Matrices - Chapter 7 in Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications, 2nd Edition edited by Richard B. Cole (2010)
• Bio-MEMS Devices for Proteomics - in Bio-MEMS: Technologies and Applications edited by Wanjun Wang and Stephen A. Soper (2006)
• Mass Spectrometry of Nucleic Acids - Chapter 7 in Genomic Technologies: Present and Future edited by David J. Galas and Stephen J. McCormack (2002)
• Advances in Nucleic Acid and Protein Analyses, Manipulation, and Sequencing - edited by Patrick A. Limbach, John C. Owicki, Ramesh Raghavachari and Weihong Tan (2000)
Jan 6, 2022
Peer-Reviewed Publications
The majority of our peer-reviewed research publications can be accessed by searching PubMed.
• Search for Limbach Group Publications via PubMed
• Search for Free-text Limbach Group Publications via PubMedCentral
Many research publications can also be accessed via GoogleScholar.
• Search for Limbach Group Publications via Google Scholar
The complete listing of Limbach Group Publications can be accessed below.